In the rapidly evolving landscape of biomedical research, the demand for precise, efficient, and scalable gene editing solutions is paramount. However, this requires a high level of expertise as well as resources and time; so, should researchers who may not have extensive experience in gene editing try and optimize and carry it out themselves? Or is it cheaper and quicker to outsource this service?
At DefiniGEN, we are proud to be able to offer a wide range of gene editing solutions, offering advanced CRISPR/Cas9-based gene editing services tailored for disease modeling. How do we do it? What do we offer exactly? What is our workflow? Continue reading to find out the answer to all these questions and 4 reasons why you should partner with us.
Our deep expertise in working with induced pluripotent stem cells (iPSCs) and CRISPR-based genome editing sets us apart. Our ability to handle even the most challenging iPSC lines ensures efficient editing with high viability and minimal off-target effects. This is critical for generating disease models that faithfully recapitulate human pathophysiology.
We have been working with iPSCs and iPSC-derived cells for over a decade, we’ve honed our techniques and protocols to ensure that our cell products carry the exact edits requested and pass our own stringent quality control measures.
From cell line evaluation to final delivery, our experts adhere to a structured and transparent workflow:
This end-to-end validation provides researchers with a high degree of confidence in the integrity of the resulting models.
It only takes four weeks to go from nucleofection to clone banking, allowing us to help accelerate your research timelines without compromising quality. Bi-weekly updates and a comprehensive final report ensure transparency and facilitate strategic planning for downstream experimentation.
We offer flexible gene editing approaches tailored to the research objectives, including gene knockouts, knock-ins, point mutations, and more complex allelic modifications. This versatility supports a wide spectrum of disease modeling applications, from monogenic disorders to polygenic traits, enabling researchers to create models aligned precisely with their investigative goals.
By combining technical rigor with customized services and expert collaboration, we empower researchers to generate highly accurate and biologically meaningful disease models. This makes DefiniGEN an invaluable partner for advancing discovery in fields such as regenerative medicine, drug development, and mechanistic disease research.