DefiniGEN’s induced pluripotent stem cell (iPSC) differentiation platform generates high quality wild-type and disease cell models. We can produce highly functional human pancreatic cells predominantly composed of insulin-secreting beta cells. We provide off-the-shelf iPSC derived pancreatic cells, but we also offer the ability to model various diseases.
The cells have similar function to primary cells including donor genetics, karotype and cell metabolism. They exhibit a robust Glucose Stimulated Insulin Secretion response and they also respond to key reference drugs such as GLP-1 and Exenatide.
Pancreatic WT Pancreatic MODY3 Pancreatic Neonatal Diabetes
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