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Human cell disease modelling

Robust human endodermal differentiation from iPSC

Generate metabolic disease phenotypes in primary-like human cells using the best-in-class iPSC differentiation platform. Preclinical modelling of orphan diseases using client specified gene-editing approaches

Welcome to DefiniGEN

DefiniGEN are a Cambridge UK company providing highly functional disease model human cells including hepatocytes, pancreatic beta cells and intestinal organoids.

Our proprietary platform technology OptiDIFF delivers our products and custom services including induced Pluripotent Stem Cell (iPSC) generation, CRISPR-Cas9 gene editing, iPSC differentiation and custom disease model development. The provision of high quality human-like cell products with a mature phenotype enables you to accelerate your research and optimize your workflow.