Intestinal Organoids
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MASH
Development of an iPSC-derived hepatocyte and hepatic stellate cell co-culture model for MASH)
In this poster, we showcase the development of a 2D...
Disease Modeling
Introducing our Disease Modeling services
Ulti-HEP: Wild-type Hepatocyte
iPSC-hepatocyte organoids as a novel platform
Abstract Adeno-associated virus (AAV) vectors are...
Toxicology Screening
Induced pluripotent stem cell (iPSC)-derived hepatocytes demonstrate functional Phase I and Phase II drug metabolism and can accurately predict drug-induced liver injury (DILI)
In this poster, we show that Ulti-HEP offers a superior...
Intestinal Organoids
Intestinal Organoid brochure
DefiniGEN intestinal organoids, Def-INT, provide a...
Toxicology Screening
Toxicology Screening Case Study
DefiniGEN's iPSC-derived hepatocytes, Ulti-HEP, offer...
A1ATD
iPSC-derived hepatocytes accurately recapitulate population diversity in alpha-1-antitrypsin deficiency and offer a novel in vitro model for large-scale drug efficacy screening studies
Background Alpha-1 antitrypsin deficiency (A1ATD) is a...
Urea Cycle Disorders
Ornithine transcarbamylase (OTC)
DefiniGEN human iPSC-derived Ornithine transcarbamylase...
Ulti-HEP: Wild-type Hepatocyte
Hepatocyte cell functionality
DefiniGEN’s proprietary differentiation protocol...
Toxicology Screening
Development of optimised human iPSC-derived hepatocytes with improved liver function for in vitro metabolic disease modelling and toxicity studies
Abstract Background & Aims Liver disease is a rising...
Ulti-HEP: Wild-type Hepatocyte
Modeling Disease with Human Inducible Pluripotent Stem Cells
Understanding the physiopathology of disease remains an...
Ulti-HEP: Wild-type Hepatocyte
Production of hepatocyte-like cells from human pluripotent stem cells
Large-scale production of hepatocytes from a variety of...
Ulti-HEP: Wild-type Hepatocyte
Generation of Hepatocytes from Pluripotent Stem Cells for Drug Screening and Developmental Modeling
Hepatocytes produced from the differentiation of human...
Ulti-HEP: Wild-type Hepatocyte
Discover how iPSC derived cells can be used to support the development of drug and gene therapies
A considerable roadblock in the successful triaging of...
Toxicology Screening
Using iPSC-Derived Hepatocyte Models for Disease Modeling and Predictive Toxicology Screening
In this GEN webinar, our speakers will present new...
Ulti-HEP: Wild-type Hepatocyte
Ulti-HEP Functionality
DefiniGEN’s proprietary differentiation protocols...
Intestinal Organoids
Generation of multipotent foregut stem cells from human pluripotent stem cells
Human pluripotent stem cells (hPSCs) could provide an...
